Pat studied at Bangor University where he obtained his MChem degree in Chemistry. Pat first worked with the group in the summer of his 3rd year where he undertook a summership placement investigating cancer prodrug therapy. Pat returned to the group during his final year to work on his masters project where he focused on the suitability of a range of enzymes for their use in MNDEPT. Now back working with the group as a P.hD. student funded by the Life Sciences Research Network Wales, in the field of chemotherapy treatments. Pat already has his first paper and is training to lead this area of research in the field of cancer prodrug therapy.
- S. D. Anderson, R. J. Hobbs, V. V. Gwenin, P. Ball, L. A. Bennie, J. A. Coulter, and C. D. Gwenin, Cell Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy, Journal of Functional Biomaterials, (2019), 10(4), 45 DOI.org/10.3390/jfb10040045
- P. Ball, E. Thompson, S. Anderson, V. Gwenin, C. Gwenin, Time dependant HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase, European Journal of Pharmaceutical Sciences, 127 (2019) 217-224 DOI.org/10.1016/j.ejps.2018.11.001
- V. V. Gwenin, P. Paramasivan, J. Halliwell, P. Ball, G. Robinson, C. D. Gwenin, (2015). Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug, Biochem Pharmacol, 98, 392-402. DOI: 10.1016/j.bcp.2015.09.01
School of Chemistry, Bangor University, Bangor, Gwynedd, LL57 2UW, UK
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