Team members – Vanessa Gwenin


Research scientists / postdoctoral researchers:


website picVanessa Gwenin

Vanessa is a Research Officer currently working on both a serology test for Buruli Ulcerans and on the novel drug delivery system aimed at cancer chemotherapy. Van initially joined the team in 2009 in which she contributed to the intellectual property on both TB detection and Cancer prodrug therapy. After an enjoyable maternity leave, she has returned part-time to help drive both projects forward and provide grant and research support.

Education:
2010 – Entry certificate in welsh second level: The use of welsh, Bangor University
2008 – MS.c (Distinction): Biochemistry, University of Pretoria, SA
2006 – BS.c (Hons) with Distinction: Biochemistry, University of Pretoria, SA
2005 – BS.c Biochemistry (Distinction)

Papers:

  • P. Ball, E. Thompson, S. Anderson, V. Gwenin, C. Gwenin, Time dependant HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase, European Journal of Pharmaceutical Sciences, 127 (2019) 217-224 DOI.org/10.1016/j.ejps.2018.11.001
  • V. V. Gwenin, P. Paramasivan, J. Halliwell, P. Ball, G. Robinson, C. D. Gwenin, (2015). Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug, Biochem Pharmacol, 98, 392-402. DOI: 10.1016/j.bcp.2015.09.01
  • V. V. Gwenin, C. D. Gwenin, and M. Kalaji, (2011), Colloidal Gold Modified with a Genetically Engineered Nitroreductase: Toward a Novel Enzyme Delivery System for Cancer Prodrug Therapy, Langmuir, 27: 14300-14307. DOI: 10.1021/la202951p
  • M. Beukes, Y. Lemmer, M. Deysel, J. R. Al Dulayymi, M. S. Baird, G. Koza, M. M. Iglesias, R. R. Rowles, C. Theunissen, J. Grooten, G. Toschi, V. V. Roberts, L. Pilcher, S. Van Wyngaardt, N. Mathebula, M. Balogun, A. C. Stoltz, J. A. Verschoor, (2010), Structure–function relationships of the antigenicity of mycolic acids in tuberculosis patients, Chemistry and Physics of Lipids, 163: 800-808.
  • Y. Benadie, M. Deysel, , G. S. Siko, V. V. Roberts, S. van Wyngaardt, S. T. Thanyani, G. Sekanka, A. M. C. Ten Bokum, L. A. Pilcher, J. Grooten, M. S. Baird, J. A. Verschoor, (2008), Cholesteroid Nature of Free Mycolic Acids from M. tuberculosis, Chemistry and Physics of Lipids, 152: 95-103.
  • S. T. Thanyani, V. V. Roberts, D. G. R. Siko, P. Vrey, J. A. Verschoor, (2008), A novel application of affinity biosensor technology to detect antibodies to mycolic acid in tuberculosis patients, Journal of Immunological Methods, 332: 1-72.

Patents:
• Kit and method – Publication No. WO 2016/024116 A1
Compositions and Methods – Publication No. WO 2016/024118
• Drug activation carrier, WO2011026898-A2; WO 2011/026898-A3; EP2473197-A2; US 2012/232328-A1
• Method for determining the presence or absence of a biomarker – Publication No. WO 2012/153111 A1

Back to team page


Gwenin - Applied Research in Chemistry and Public Health (ARCH)

School of Chemistry, Bangor University, Bangor, Gwynedd, LL57 2UW, UK

Direct Line: 0044 1248 383741 email: c.d.gwenin@bangor.ac.uk

Applied Research in Chemistry and Public Health (ARCH)

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News: July 2019

Congratulations to and Robert, Carol, Jennifer, on the publication of their Botulinum Neurotoxins Review in Toxins

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News: June 2019

PhD Post Doc Forum group photo 3

We were delighted to attend the CALIN PhD/Post-Doc/Industry Forum, hosted by Prof. Frank Barry and the CALIN team at the National University Institute Galway.

News: June 2018

Congratulations to Simon and Vanessa on the publication of their new review

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News: April 2019

Congratulations to Simon for passing his PhD

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