Papers:

paper logos

2023

  • J. Hacking, V. Gwenin, R.J. Dacombe, M. Frimpong, R.O. Philips and C.D. Gwenin, A Single Synthetic Lipid Antigen for Improved Serological Diagnosis of Buruli Ulcer, Accepted Public Health Action, 13, 4, 173-178 (2023) DOI: https://doi.org/10.5588/pha.23.0038
  • P. Ball, E. Thompson, S. Anderson, V. Gwenin, A. Ashoorzadeh, J. Smaill and C. Gwenin, The Dinitrobenzamide Mustard Prodrugs, PR-104A and SN27686, for Use in a Novel MNDEPT Cancer Prodrug Therapy Approach, Bioscience reports, Bioscience Reports 00 1–12. (2023) DOI.org/10.1042/BSR20230627
  • A. Abd Mana, S. P. Hong, M. Rizwan, F. Arshad, C. Gwenin, M. U. Ahmed, 2023 Recent advancement in sensitive detection of carcinoembryonic antigen using nanomaterials based immunosensors, Surfaces and Interfaces, 102596, DOI.org/10.1016/j.surfin.2022.102596

2021

  • M. Rizwan and C. Gwenin, 2021 Nanomaterials in renewable energy: UV-Visible spectroscopy characterization and applications DOI.org/10.1016/B978-0-12-821709-2.00017-7

  • P. Ball, R. Hobbs, S. Anderson, E. Thompson, V. Gwenin. C. Von Ruhland, C. D. Gwenin, The YfkO nitroreductase from Bacillus Licheniformis on gold-coated superparamagnetic nanoparticles: Towards a novel directed enzyme prodrug therapy approach, Pharmaceutics 13, (4), 517 (2021) DOI.org/10.3390/pharmaceutics13040517

  • J. Davies, C. Thomas, R. Mohammad, C. Gwenin, Development of electrochemical DNA biosensor for equine hindgut acidosis detection, Sensors  21, 2319 (2021) DOI.org/10.3390/s21072319
  • C. Thomas and C. D. Gwenin, The role of nitroreductases in resistance to nitroimidazoles, Biology, 10(5), 388 (2021); https://doi.org/10.3390/biology10050388
  • A. J. Heeroma, J. Toffrey and C. D. Gwenin, Approaches towards the detection of Sepsis: A review, Int J Biomed Clin Anal. 1(1):01-16, (2021)

2020

  • A. Jones, S. Fitch, C. Davies, J. Al Dulayymi, C. Gwenin, J. Gibbons, P. Williams, M. Baird, Elevated serum antibody responses to synthetic mycobacterial lipid antigens among UK farmers: an indication of exposure to environmental mycobacteria? RSC Medicinal Chemistry, 12, 213-221 (2020) DOI.org/10.1039/domd00325E
  • C. Jones and C. D. Gwenin, Cortisol level dysregulation and its prevalence – Is it nature’s alarm clock? Physiological Reports, 8, 14644, (2020) DOI.org/10.14814/phy2.14644
  • P. Ball, J. Halliwell, S. Anderson, V. Gwenin, C. Gwenin, Evaluation of two Xenobiotic Reductases from Pseudomonas putida for their suitability for a novel MNDEPT cancer prodrug therapy approach, MicrobiologyOpen. 00: 1– 10, (2020) DOI.org/10.1002/mbo3.1110
  • A. J. Heeroma and C. D. Gwenin, Development of solid-phase RPA on a lateral flow device for the detection of pathogens related to Sepsis, Sensors, 20(15), 4182, (2020) DOI.org/10.3390/s20154182

2019

  • S. D. Anderson, R. J. Hobbs, V. V. Gwenin, P. Ball, L. A. Bennie, J. A. Coulter, and C. D. Gwenin, Cell Penetrating Peptides as a Tool for the Cellular Uptake of a Genetically Modified Nitroreductase for use in Directed Enzyme Prodrug Therapy, Journal of Functional Biomaterials, 10(4), 45, (2019) DOI.org/10.3390/jfb10040045
  • R. Hobbs, C. Thomas, J. Halliwell, C. Gwenin, Rapid Detection of Botulinum Neurotoxins – A Review, Toxins 11(7), 418, (2019) DOI.org/10.3390toxins11070418
  • S. Anderson; V. V Gwenin; C. Gwenin, Magnetic functionalized nanoparticles for biomedical, drug delivery and imaging applications, Nanoscale Research Letters, 14:188, (2019) DOI.org/10.1186/s11671-019-3019-6
  • P. Ball, E. Thompson, S. Anderson, V. Gwenin, C. Gwenin, Time dependant HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase, European Journal of Pharmaceutical Sciences, 127, 217-224 (2019) DOI.org/10.1016/j.ejps.2018.11.001

2018

  • V. O. Ebuele, D. G. Congrave, C. D. Gwenin and V. Fitzsimmons-Thoss, Development of a Cobalt Electrode for the Determination of Phosphate in Soil Extracts and Comparison with Standard Methods, Analytical Letters, Volume: 51, Issue: 6  Pages: 834-848, (2018) DOI.org/10.1080/00032719.2017.1360899

2017

  • A. Jones, M. Pitts, J’a R. Al Dulayymi, J. Gibbons, A. Ramsay, D. Goletti, C. D. Gwenin, and M. S. Baird, New synthetic lipid antigens for rapid serological diagnosis of tuberculosis, PLOS ONE, August 14, (2017) DOI:10.1371/journal.pone.0181414

2016

  • M. Ali, G. Koza, R. T. Hameed, R. Rowles, C. Davies, J. R. Al Dulayymi, C. D. Gwenin, M. S. Baird, The synthesis of single enantiomers of trans-alkene containing mycolic acids and related sugar esters, Tetrahedron, 72, (45), 7143–7158 (2016) DOI:10.1016/ j.tet.2016.08.089
  • M. O. Mohammed, M. S. Baird, J’aR. Al Dulayymi, A. Jones, C. D. Gwenin, Arabino Mycolates from Synthetic Mycolic Acids, Tetrahedron, 72 (22), 2849–2857 (2016) DOI: 10.1016/j.tet.2016. 03.083

2015

  • V. Gwenin, P. Paramasivan, J. Halliwell, P. Ball, G. Robinson, C. D. Gwenin, Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug, Biochemical Pharmacology, 98, 392-402 (2015) DOI: 10.1016/j.bcp.2015.09.01
  • C. Savage,  N. Buckley, J. Halliwell, and C. D. Gwenin, Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy,  Toxins, 7, 1544-1555 (2015) DOI:10.3390/toxins7051544

2014

  • P. Connell, J. Holliman, E. W. Jones, L. Furnell, C. Kershaw, M. L. Davies, C. D. Gwenin, M. B. Pitak, S. J. Coles and G. Cooke, Multiple linker Half-squarylium Dyes for Dye-Sensitized Solar Cells; Are Two Linkers Better than One?, Journal of Materials Chemistry A, 3, 2883-2894 (2014) DOI:10.1039/C4TA06896C
  • J. Halliwell, A. C. Savage, N. Buckley and C. D. Gwenin, Electrochemical Impedance Spectroscopy Biosensor for Detection of Active Botulinum Neurotoxin. Sensing and BioSensing Research, 2, 12-15 (2014) DOI:10.1016/j.sbsr.2014.08.002
  • P. Holliman, A. Connell, M. L. Davies, S. Weiss, C. D. Gwenin, M. Pitak, P. Horton, S. Coles and G. Cooke, A Study of Dye Anchoring Points in Halfsquarylium Dyes for DyeSensitized Solar Cells, Journal of Materials Chemistry A, 2 (11), 4055 – 4066 (2014) DOI: 10.1039/C3TA15278B

2013

  • J. Halliwell and C. Gwenin, A Label Free Colorimetric Assay for the Detection of Active Botulinum Neurotoxin Type A by SNAP-25 Conjugated Colloidal Gold. Toxins, 5, 1381-1391 (2013) DOI:10.3390/toxins5081381
  • L. Barrault, Bedel, E. Charikane, L. Gunnarsen, C. Gwenin, J. Jones, P. Lieberzeit, A. Rowley, T. Soto, S. Thollon, B. Thorstensen, S. Traberg-Borup and N. Wright, Nanosecure: Advanced nanotechnological detection and detoxification of harmful airborne substances for improved public security. Actualite Chimique, 378-379, 27-34. (2013)
  • C. French and C. Gwenin, Biosensors in bioprocess monitoring and control. In Fermentation Microbiology and Biotechnology, 3rd edition, ed. El-Mansi, M., CRC Press 2011, Boca Raton, Print ISBN: 978-1-4398-5579-9 eBook ISBN: 978-1-4398-5581-2 DOI: 10.1201/b11490-14

2011

  • V. Gwenin, C. D. Gwenin and M. Kalaji, Colloidal Gold Modified with a Genetically Engineered Nitroreductase: Towards a Novel Enzyme Delivery System for Cancer Prodrug Therapy. Langmuir, 27 14300 (2011) DOI: 10.1021/la202951p
  • M. Morozova, P. Kluson, J. Krysa, C. Gwenin, O. Solcova, Oxalic acid sensors based on sol-gel nanostructured TiO2 films. Journal of Sol-Gel Science and Technology. 58 (1) 175 (2011) DOI: 10.1007/s10971-010-2374-7
  • M. Cude, and C. D. Gwenin, Development of gold coated superparamagnetic iron oxide nanoparticles for nitroreductase delivery. ECS Trans. 33, 79 (2011) DOI: 10.1149/1.3583517

2010

  • C. D. Gwenin, M. Kalaji, C. M. Kay, and P. A. Williams, A kinetic analysis of three modified novel nitroreductases for potential use in explosive detection. Biodegradation 22, 12, 2869-2875 (2010) DOI: 10.1007/s10532-010-9418-0

2009

  • M. Kalaji, C. D. Gwenin and C. Kay, The development of an amperometric biosensor based on the assembly of genetically engineered enzymes for the detection of explosives. ECS Trans 19, 93-102, (2009) DOI: 10.1149/1.3118541

2008

  • C. D. Gwenin, M. Kalaji, C. M. Kay, P. A. Williams and D. N. Tito, An in situ amperometric biosensor for the detection of vapours from explosive compounds. Invited article for the special issue of Detection for Security in The Analyst, 133, 621 – 625 (2008) DOI: 10.1039/B713269G

2007

  • C. D. Gwenin, M. Kalaji, P. A. Williams and R. M. Jones, The orientationally controlled assembly of genetically modified enzymes in an amperometric biosensor. Biosensors and Bioelectronics, Chem and Biosensing Transistors: from materials to systems, 22, 2869-2875, (2007) DOI: 10.1016/j.bios.2006.12.012
  • C. D. Gwenin, J. P. Jones, M. Kalaji, T. J. Lewis, J. P. Llewellyn and P. A. Williams, Viscoelastic change following adsorption and subsequent molecular reorganisation of a nitroreductase enzyme on a gold surface: A QCM study. Sensors and Actuators B: Chemical, 126(2): 499-507, (2007) DOI:10.1016/j.snb.2007.03.037

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