Previous work between Bangor and Sophimark has shown that a dye can be manipulated within a solid matrix material. As part of the CALIN program, continued work with Sophimark will allow rigorous evaluation to be conducted in order to show that a fully integrated diagnostic device can be developed. Partners: Sophimark Ltd, Bangor University & University College Cork
The project originated from initial work conducted in 2012 between Bangor and Sophimark on the manipulation of molecules within solid matrix material. The first data sets conducted at Bangor showed that a dye placed within a solid matrix could be controlled accurately within a specific area of the matrix. Follow-on experiments with nucleic acid based bioassays showed that molecular based reactions could be conducted within a solid matrix. These initial experiments illustrated the basic proof of principle. However, a rigorous evaluation needs to be conducted in order to show that a fully integrated device can be developed, where sample preparation, nucleic acid amplification, and detection, can all be performed within a single solid matrix-based device.
This project will be carried out in collaboration with SOPHIMARK and University College Cork The project has been part-funded by the European Regional Development Fund through the Ireland Wales Cooperation programme
School of Chemistry, Bangor University, Bangor, Gwynedd, LL57 2UW, UK
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